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pentobarbital will decrease the level or effect of imatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.pentobarbital will decrease the level or effect of ritonavir samhälle affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Bildskärm.Nursing mothers: Caution should be exercised when a barb